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To assign genotypes to individuals on a pedigree. In these pedigrees, it is common to observe a higher prevalence of the disorder among males compared to females. Men possess only one x chromosome
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The disease is brought on by a single recessive gene on that x chromosome Hemophilia a gained notoriety in early studies of human genetics because it affected at least 10 males among the descendants of queen victoria, who was a carrier. The other half of the male xy gene pair is the y chromosome.