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From the research serotonin syndrome and concerta (methylphenidate) concerta, also known as methylphenidate, is a central nervous system stimulant commonly used to treat attention deficit hyperactivity disorder (adhd) and certain cases of narcolepsy. Mesh terms adolescent central nervous system stimulants / adverse effects* female humans methylphenidate / adverse effects* selective serotonin reuptake inhibitors / adverse effects* serotonin syndrome / chemically induced* sertraline / adverse effects* It most commonly occurs when certain antidepressants, migraine medications, opioids, or illicit drugs are taken alone in high doses or, more often, in combination.
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Even though the methylphenidate dose was minimal in the present case, the synergic effect of sertraline and methylphenidate probably induced serotonin syndrome Although commonly called serotonin syndrome, serotonin toxicity is a more accurate term, since toxicity presents on a spectrum rather than as a defined set of symptoms (i.e., a syndrome) Thus, the augmentation of ssri therapy with methylphenidate requires consideration of possible development of serotonin syndrome.
Serotonin syndrome is reported as a side effect among people who take ritalin (methylphenidate hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take concerta, and have autism spectrum disorder
The phase iv clinical study analyzes which people have serotonin syndrome when taking ritalin.