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Empty, anastomosing spaces within collagen usually not mass forming rb1 positive by immunohistochemistry and lacks del 13q14 similar immunoprofile (cd34 positive, desmin positive [variable], er, pr and ar positive) solitary fibrous tumor Fibroadenomatoid change is a benign, often incidental finding in a background of fibrocystic changes Stat6 positive (pathol res pract 2018;214:1544)
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Hamartoma is a well circumscribed, often encapsulated mass composed of normal but disorganized components of breast tissue Pash (pseudoangiomatous stromal hyperplasia) is specific to breast int ra lobular surrounds acini in tdlus compared to interlobular stroma, looser in appearance or even myxoid often small numbers of inflammatory cells lesions arising here are biphasic involving epithelial and stromal components, including fibroadenoma, phyllodes tumor Columnar cell lesions of breast are enlarged terminal duct lobular units (tdlus) with irregularly dilated acini lined by columnar epithelial cells
