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In liver pathology, a ground glass hepatocyte, abbreviated ggh, is a liver parenchymal cell with a flat hazy and uniformly dull appearing cytoplasm on light microscopy This appearance corresponds to a proliferated smooth endoplasmic reticulum ultrastructure. The cytoplasm's granular homogeneous eosinophilic staining is caused by the presence of hbsag.
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Clinical history revealed medication use in nine (82%) patients including nsaids, steroids, and chemotherapy. In this study, we demonstrate that the reason for the ground glass phenotype of hepatocytes in the liver of patients with chronic hepatitis b (chb) and hbs transgenic mice is a complex formation between hbs and lds in the er. Ground glass hepatocytes (gghs) are very important in understanding hepatitis
They are special cells found in the liver, mainly seen in people with chronic hepatitis b virus (hbv) infection
These cells look glassy because they have a lot of hepatitis b surface antigen (hbsag) inside them. The ground glass hepatocyte, abbreviated ggh, is a histologic finding that is seen in medical liver pathology and usually suggest a chronic hepatitis b infection. A systematic approach to this differential and a good history can eliminate many of the causes Fibrinogen accumulation in the liver is rare and can represent both inherited and acquired disease.
