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By virtue of its overexpression in cancer and its association with tumor growth and metastasis, vimentin serves as an attractive potential target for cancer therapy Vimentin is a special protein found in certain types of cells called mesenchymal cells However, more research would be crucial to evaluate its specific role in cancer.
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Vimentin is highly expressed in metastatic cancers, and its expression correlates with poor patient prognoses Study reveals the impact of vimentin c328 on cancer behavior Vimentin staining confirms mesenchymal origin of some tumors but there are numerous exceptions, so relatively nonspecific carcinomas and epithelial tumors are usually negative but there are many exceptions thus, helps distinguish renal cell carcinoma and uterine carcinoma as part of panel
Vimentin, a major constituent of the intermediate filament family of proteins, is ubiquitously expressed in normal mesenchymal cells and is known to maintain cellular integrity and provide resistance against stress
Vimentin is overexpressed in various epithelial cancers, including prostate cancer, … This comprehensive review explores vimentin as a pivotal therapeutic target in cancer treatment, with a primary focus on mitigating metastasis and overcoming drug resistance The review delves into diverse. Here, the authors show that tumour endothelial cells can secrete vimentin as a pro.